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紫外线可切生物素化叠氮UV Cleavable Biotin-Azide
紫外线可切生物素化叠氮
UV Cleavable Biotin-Azide
  • 产品编号: EVU102

  • 相关CAS号:N/A

  • 分子式:N/A

  • 分子量:781.92

订货号 规格 价格 库存 数量 购买
EVU102 10mg ¥ 6720.00元 26

产品简介


The UV Cleavable Biotin-Azide allows the tagging of alkyne modified substrates via copper-catalyzed click chemistry.

Highlights:

* Biotin conjugate can be subsequently visualized by streptavidin Western techniques and/or enriched using streptavidin purification methods

* Captured target can be released under mild photolysis conditions (365 nm) and results in a significant decrease of background signal due to non-specifically bound proteins

* Also available: 13C6-UV-Biotin-azide(EVU151)



产品详情

产品类型/Product Type: Small Molecule    
产品名称/Name:UV Cleavable Biotin-Azide
化学式/Chemical Formula: C38H51N7O9S   
分子量/Molecular Weight:781.92  
外观形态/Format:Solid
溶解性/Solubility: DMSO, MeOH 
光解/ Photolysis:λ=365nm 
来源/Source: Synthetic
存储温度/Storage: Upon receipt store at -20C   
运输温度/Shipped:Ambient temperature     


参考文献

1. Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems. Codreanu, S. G.; Ullery, J. C.; Zhu, J.; Tallman, K. A.; Beavers, W. N.; Porter, N. A.; Marnett, L. J.; Zhang, B.; Liebler, D. C. Mol. Cell. Proteomics 2014, 13, 849.

2. An Azido-Biotin Reagent for Use in the Isolation of Protein Adducts of Lipid-Derived Electrophiles by Streptavidin Catch and Photo-Release.  Kim, H.-Y. H.; Tallman, K. A.; Liebler, D. C.; Porter, N. A. Mol. Cell. Proteomics 2009, 8, 2080.

3. Yang J, Gupta V, Tallman KA, Porter NA, Carroll KS, Liebler DC. Global, in situ, site-specific analysis of protein S-sulfenylation. Nat Protoc. 2015 Jul;10(7):1022-37. 文献链接

4. Fu L, Liu K, Ferreira RB, Carroll KS, Yang J. Proteome-Wide Analysis of Cysteine S-Sulfenylation Using a Benzothiazine-Based Probe. Curr Protoc Protein Sci. 2019 Feb;95(1):e76. 文献链接


产品说明书:auto_1455.pngUV Cleavable Biotin-Azide

细胞点击化学反应流程示意图

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